FDOK (fatty degenerative osteolysis of the jawbone) and NICO (neuralgia-inducing cavitational osteonecrosis) are chronic, silent inflammations in the jawbone. These foci often cause no local pain but can burden the entire body — they produce inflammatory mediators such as RANTES that have been linked to chronic fatigue, joint pain, autoimmune conditions and other systemic complaints.
We diagnose these conditions using 3D CBCT imaging, which reveals characteristic bone dissolution patterns. Treatment involves surgical removal of the affected bone, followed by ozone disinfection and PRF therapy to support bone regeneration.
Unfortunately, these foci are often symptom-free in the jaw area. Clues may include chronic fatigue, joint pain or unexplained complaints that no other doctor has been able to diagnose.